So Many Skin Boosters — Which One Should You Choose?

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Dec 4, 2025

If you’ve been researching ways to achieve glowing, hydrated, youthful skin, you’ve probably come across the term skin boosters. These injectable treatments are becoming increasingly popular for improving skin quality without altering your facial structure. But with so many options—SkinVive, polynucleotides, Profhilo, NCTF, and PRP—how do you choose the right one?

Below, we break down each skin booster, what it does, and who it’s best suited for.


What Are Skin Boosters?

Skin boosters are injectable treatments designed to improve hydration, texture, elasticity, fine lines, and overall radiance. Unlike dermal fillers, skin boosters don’t add volume—they enhance skin quality from within.


1. SkinVive (Hyaluronic Acid Microdroplets)

SkinVive, made by the creators of Juvederm, uses microdroplets of hyaluronic acid (HA) to boost skin hydration. It doesn’t change facial contours—it’s all about giving your skin a smoother, more luminous appearance.

Best for:

  • Dull or dehydrated skin
  • Mild texture irregularities
  • Patients wanting a quick glow without downtime

Why Choose It?

SkinVive is ideal if you want instant hydration and a dewy finish. Think of it as a long-lasting skin-plumping treatment.


2. Polynucleotides (PN/PNN Skin Regeneration)

Polynucleotides are derived from purified DNA fragments (usually salmon DNA) that stimulate tissue repair, collagen production, and deep hydration.

Benefits:

  • Improves elasticity
  • Reduces inflammation and redness
  • Enhances skin regeneration
  • Great for under-eyes and crepey skin

Best for:

  • Sensitive or compromised skin
  • Under-eye fine lines and dark circles
  • Early signs of aging

Why Choose It?

Polynucleotides are excellent if you want healing, regeneration, and long-term skin improvement, not just hydration.


3. Profhilo (Bio-Remodeling HA)

Profhilo is one of the most famous skin boosters globally. It contains a high concentration of hyaluronic acid, but unlike SkinVive, it spreads under the skin.

Benefits:

  • Firms and tightens the skin
  • Improves laxity
  • Hydrates from within

Best for:

  • hydration
  • Crepey skin on face, neck, and hands

Why Choose It?

Profhilo is perfect if your goal is skin plumping+ hydration in one treatment.


4. NCTF (Nutrient-Rich Mesotherapy Cocktail)

NCTF by Fillmed is a mesotherapy formula combining:

  • Hyaluronic acid
  • 50+ vitamins
  • Amino acids
  • Minerals
  • Antioxidants

This “skin food” cocktail nourishes and revitalizes the skin from inside out.

Benefits:

  • Improves brightness
  • Smooths fine lines
  • Boosts skin metabolism
  • Great for overall skin quality

Best for:

  • Dull, tired, or nutrient-depleted skin
  • Smokers or stressed skin
  • Early signs of aging

Why Choose It?

Choose NCTF if you want full-spectrum rejuvenation and a refreshed skin appearance.


5. PRP (Platelet-Rich Plasma)

PRP, commonly known as the “vampire facial,” uses your own blood plasma rich in growth factors.

Benefits:

  • Stimulates natural collagen
  • Improves acne scarring
  • Reduces fine lines
  • Enhances texture

Best for:

  • Patients wanting a completely natural treatment
  • Acne scars or rough texture
  • Early aging signs

Why Choose It?

Because PRP uses your own platelets, it’s ideal for people seeking natural regeneration without synthetic products.

How to Choose the Right Skin Booster

Skin ConcernBest Treatment
Deep hydration + glowSkinVive
Under-eye issues, inflammation, healingPolynucleotides
Skin laxity + hydrationProfhilo
Dull, stressed skin needing nutrientsNCTF
Texture issues, scars, natural regenerationPRP

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